Top 10 Best CBD Creams for Pain | April 2021 |

CBDNerds Staff
Authored: Sep 11, 2018
Updated: Apr 6, 2021
Best CBD Creams for Pain

Best CBD Creams for Pain ‌‌|‌‌ April 2021

The National Institutes of Health reports that cannabidiol (CBD) has excellent pain relief qualities and notes that topical CBD solutions are an effective and safe way to control neuropathic pain. CBD is also an effective painkiller for those who have not found relief from traditional painkillers or treatments.


CBD topicals tend to be the most popular for people struggling with pain as they allow you to target specific areas of the body. For this reason, I’ve devised a list of the 10 best CBD creams for pain relief.


All of these products were bought and tested on a shoulder recovering from a torn rotator cuff that was very painful. Each of the creams has its pros and cons which I'll highlight below. The CBD creams that have made it on this list are sold online by some of the biggest and best brands.


Top Ranking CBD Creams for Pain

1.) Charlotte's Web

Charlotte's Web CBDMedic Active Sport Pain Relief Ointment

Rating 5/ 5

Extract Type: Broad-spectrum

Total CBD Range: 200mg

Potency Range: Not mentioned

Price Range: $39.99

Value ($/mg): $0.20 per mg

THC Content: 0.0%

Lab Report: See Here

Scent Variations: 6

Potency Variations1


Charlotte’s Web Pros:

  • Variety of pain relief topicals for different ailments
  • Each topical uses a variety of all-natural ingredients
  • One of the top CBD brands currently on the market


Charlotte’s Web Cons:

  • Lower CBD dosage compared to competitors


Charlotte's Web partnered with CBDMedic to develop a line of pain relief topicals that are some of the finest on the market. Each is made using a specific formula to help with specific ailments such as arthritis, active sports pain, and foot pain. Not to mention, the pain-relieving balm will also moisturize your skin thanks to Charlotte’s Web’s ingredient selection.


Another benefit of Charlotte's Web hemp topicals is that they are reasonably priced compared to many other similar CBD products, and you only need to rub a small amount onto the affected joint or muscle to start feeling its effects. The company also offers a wide variety of other hemp and CBD products, including creams, capsules, oils, and pet products.


2.) Green Roads

Green Roads CBD Muscle & Joint Cream

Rating 5/ 5

Extract Type: Broad-spectrum

Total CBD Range: 50mg - 750mg

Potency Range: Not mentioned

Price Range: $11.99 - $69.99

Value ($/mg): $0.09 - $0.24 per mg

THC Content: 0.0%

Lab Report: See Here

Scent Variations: 1

Potency Variations4


Green Roads Pros:

  • Offered in a Cool Relief or a Heat Relief
  • Offered in a travel-sized container (50mg total CBD)


Green Roads Cons:

  • Higher potencies only offered in roll-on, not cream


Green Roads Muscle & Joint Relief Cream contains 150mg of broad-spectrum CBD per ounce, extracted from American-grown hemp and infused into a soothing, non-greasy cream. The pain-relieving cream also contains chamomile extract and lavender oil, offering a soothing, relaxing scent as you rub it on.


Green Roads offers its Muscle & Joint Relief topical in both 150mg and 350mg potencies, so you can choose the strength that suits the relief you need. The company also released a 750mg roll-on recently for extra relief. Whichever dose you choose, you can look forward to using a product that's reliable and safe, which is one of the benefits of buying from a company founded by a pharmacist.


In addition to the soothing relief this Muscle & Joint Relief Cream promises, Green Roads offers a variety of other CBD products.


3.) CBDistillery

CBDistillery CBDol CBD Salve

Rating 4.5/ 5

Extract Type: Broad-spectrum

Total CBD Range: 500mg - 1,000mg

Potency Range: Not mentioned

Price Range: $20.00 - $35.00

Value ($/mg): $0.03 - $0.04 per mg

THC Content: 0.0%

Lab Report: On individual product pages

Scent Variations: 1

Potency Variations2


CBDistillery Pros:

  • Best priced item on our list (on a per milligram basis)
  • Offers a subscription service to help you save
  • Certified by the U.S. Hemp Authority


CBDistillery Cons:

  • CBD pain relief only comes as a stick, not cream


CBDistillery is a Colorado-based company that uses 100% natural hemp from plants that are free of pesticides and GMOs. This CBD pain relief stick contains either 500mg or 1,000mg of cannabidiol and provides immediate relief for muscle and joint pain.


Not only does CBDistillery Topical CBD Salve contain the anti-inflammatory qualities of cannabidiol, but it also includes several other natural anti-inflammatory oils such as eucalyptus, peppermint, and lavender. CBDol is a full-spectrum salve that contains all the necessary cannabinoids to get the full benefits of the hemp plant. This full-spectrum hemp is popular for arthritis pain.


In terms of a CBD pain relief cream, CBDistillery was close to being my favorite, except there is a slightly off smell I didn't like and the container is smaller than the others. In regards to rubbing it on and the relief, this was probably the best product I tried. It is priced slightly higher than the Endoca Salve, but if you decide on this one, you won't be disappointed. The rub-on is very smooth and not too oily.



SOL CBD CBD Infused Herbal Balm

Rating 4.5/ 5

Extract Type: Full-spectrum

Total CBD Range: 250mg

Potency Range: Not mentioned

Price Range: $49.99

Value ($/mg): $0.20 per mg

THC Content: <0.3%

Lab Report: On individual product pages

Scent Variations: 1

Potency Variations1



  • Contains CBD and 12 other all-natural ingredients to ease pain
  • Can be purchased in a pack of 1, 2, or 3
  • Offers subscription service to help you save



  • One of the pricier CBD topicals on our list


SOL CBD Hemp-Infused Balm blends CBD oil with 12 other essential oils and natural herbal extracts. This CBD pain relief cream uses ucuuba butter which also has anti-inflammatory and antiseptic properties. Ucuuba butter is used for treating acne, arthritis, eczema, rheumatism, and skin ulcerations. The Nevada-based company offers a 60-day money-back guarantee.


SOL CBD’s balm is definitely one of my favorite CBD creams I've tried for its smooth rub-on and pleasant smell - this would actually make a great massage oil. It did slightly help with my muscle pain but wasn't as strong as the other options. It does come in a larger case so lasts longer, but on the downside, it has less CBD than the above pain relief creams I tested.


5.) Pure Science Lab

Pure Science Lab KannaFreeze Full Spectrum CBD Hemp Extract Pain Relief Cream

Rating 4/ 5

Extract Type: Full-spectrum

Total CBD Range: 250mg - 500mg

Potency Range: Not mentioned

Price Range: $29.95 - $159.95

Value ($/mg): $0.12 per mg

THC Content: <0.3%

Lab Report: See Here

Scent Variations: 1

Potency Variations1


Pure Science Lab Pros:

  • Made using a number of all-natural ingredients (such as aloe vera extract and grapeseed oil extract) to ensure pain relief
  • Can be purchased in multiple tubes to help you save


Pure Science Lab Cons:

  • Higher CBD range means larger tube, not higher potency


KannaFreeze Pain Cream makes it to the top five based on customer feedback, effectiveness, and price. This CBD cooling cream contains full-spectrum CBD extract derived entirely from industrial hemp oil. It also contains 7% menthol which enhances the effects of muscle pain relief. This is popular among athletes, weight lifters, and long-distance runners.


6.) cbdMD

cbdMD CBD Recover Cream

Rating 4/ 5

Extract Type: Broad-spectrum

Total CBD Range: 300mg - 3,000mg

Potency Range: Not mentioned

Price Range: $29.99 - $149.95

Value ($/mg): $0.05 - $0.10 per mg

THC Content: 0.0%

Lab Report: See Here

Scent Variations: 1

Potency Variations4


cbdMD Pros:

  • Very affordable compared to competitors
  • Can be purchased as a roll-on or squeezy tube
  • Offers a subscription service to help you save


cbdMD Cons:

  • Broad-spectrum extract doesn’t allow for the entourage effect


cbdMD Freeze pain cream with 1,500mg CBD is among the best CBD pain relief topicals I have tested. You can purchase smaller dosages in 300mg and 750mg, but if you are in serious pain, you'll want the 1,500mg or the higher potency of 3,000mg. This topical just needs a shake and you can roll it on wherever you're feeling muscle pain, arthritis, or any other tension related to your joints.


The product uses broad-spectrum CBD along with CBG, CBDv, CBN, and more. Because there's no THC, you won't get any sort of high from this CBD topical. What really helps with the muscle pain is the menthol USP natural 4%, which is what gives you that icy hot feeling. Meanwhile, the CBD helps with its anti-inflammatory properties. If you purchase this pain relief topical, you'll want to use it up to four times daily.


cbdMD is not only a top trusted pain topical provider but it also makes it onto the list for having great customer service via live chat and fast shipping. However, it is the top-priced CBD brand we've reviewed.


7.) Receptra Naturals

Receptra Naturals Serious Relief + Arnica Targeted CBD Topical

Rating 4/ 5

Extract Type: Full-spectrum

Total CBD Range: 400mg - 800mg

Potency Range: Not mentioned

Price Range: $44.99 - $71.99

Value ($/mg): $0.09 - $0.11 per mg

THC Content: <0.3%

Lab Report: See Here

Scent Variations: 1

Potency Variations1


Receptra Naturals Pros:

  • Offers a variety of pain relief topicals (only Serious Relief + Arnica reviewed in the table above)
  • Made using all-natural ingredients


Receptra Naturals Cons:

  • Larger CBD range means larger size, not higher potency


Receptra Naturals Serious Relief + Arnica Targeted Topical is available in two sizes: 1.25oz (400mg CBD) and 2.5oz (800mg CBD). The non-greasy formula provides excellent, fast relief from joint and muscle pain. Receptra Naturals Targeted Topical is also made with essential oils such as jasmine and arnica to help you relax.


This product was one of my favorite CBD pain relief topicals for a variety of reasons. It came in a mid- to large-size container, meaning you won't run out in a week. It smelled the best in my opinion as the ingredients are pure and natural with minimal additions. It rubbed on smoothly and would actually make great massage oil for massaging a sore muscle. It was extremely helpful in relieving pain in my shoulder, but if there are any knocks on this product, it would be that it rubs on quite oily.


8.) Palmetto Harmony

Palmetto Harmony Heal CBD Topical Lotion

Rating 4/ 5

Extract Type: Full-spectrum

Total CBD Range: 300mg - 600mg

Potency Range: Not mentioned

Price Range: $29.99 - $34.99

Value ($/mg): $0.06 - $0.10 per mg

THC Content: <0.3%

Lab Report: See Here

Scent Variations: 1

Potency Variations2


Palmetto Harmony Pros:

  • Palmetto Harmony’s Menthol Muscle Rub has one of the best deals on our list
  • Topicals are offered in a bundle set with other CBD products


Palmetto Harmony Cons:

  • Muscle Rub can only be purchased as a roll-on, not cream


Palmetto Harmony’s Menthol Muscle Rub combines simple ingredients with high-CBD hemp oil to create a soothing cream that can be applied as needed. This pain-relieving cream is particularly good for sensitive individuals as it only contains a few ingredients and is 100% fragrance-free. Each 3oz jar is packed with 600mg of CBD, and it must be kept at temperatures below 75 degrees, otherwise, it can liquefy and will need to be refrigerated to restore its usual consistency.


Palmetto Harmony is a family-run company that offers many other useful CBD products, including full-spectrum cannabis oil, capsules, and pre-filled vape pens.


9.) Endoca

Endoca Hemp Salve

Rating 4/ 5

Extract Type: Full-spectrum

Total CBD Range: 250mg - 750mg

Potency Range: Not mentioned

Price Range: $20.00 - $51.20

Value ($/mg): $0.07 - $0.08 per mg

THC Content: <0.3%

Lab Report: See Here

Scent Variations: 1

Potency Variations1


Endoca Pros:

  • GMO-free and made with all-natural ingredients
  • Offers a subscription service to help you save


Endoca Cons:

  • Total CBD range changes size of the jar, not potency


Endoca Hemp Salve is 100% organic and contains either 250mg or 750mg of CBD. This is an excellent CBD pain relief rub not only because of its potency but also because it is made with natural food-grade ingredients to ensure quality. This CBD pain relief salve is free of pesticides and GMOs and is ISO certified.


This all-natural product can heal sensitive areas of skin, like your face or chapped lips, with soothing ease, but it is also strong enough to heal broken skin and cracked heels. Dandruff and red skin are no problem for Endoca Hemp Salve because it can also help to heal mild cases of seborrheic dermatitis, plus it also has an anti-itching quality.


Endoca Hemp Salve also has anti-aging qualities, helping to prevent dry skin and wrinkles. The product makes our list for its top-quality ingredients, although just keep in mind that it's a little more difficult to rub on as it's a CBD salve as opposed to a cream. 750mg is one of the higher concentration salves you'll find.


10.) Sagely Naturals

Sagely Naturals Relief and Recovery Cream

Rating 3.5/ 5

Extract Type: Broad-spectrum

Total CBD Range: 125mg - 250mg

Potency Range: Not mentioned

Price Range: $16.99 - $29.99

Value ($/mg): $0.12 - $0.14 per mg

THC Content: 0.0%

Lab Report: See Here

Scent Variations: 1

Potency Variations1


Sagely Naturals Pros:

  • Gluten-free, vegan, cruelty-free, and made in a GMP facility
  • Made using all-natural ingredients


Sagely Naturals Cons:

  • Total CBD range changes size of the jar, not potency


Sagely Naturals’ Relief & Recovery Cream is a CBD pain relief cream that combines peppermint, menthol, and safflower seed oil with organic hemp oil. It hydrates and moisturizes while also providing refreshing, cooling pain relief. Sagely Naturals hemp cream also features Moroccan argan oil which is known for its antioxidant and anti-inflammatory qualities.


This non-greasy CBD cream is lightweight and works great for minor muscle aches and joint pain. The company ships for free when you spend more than $36, and you can save 20% off your first order if you join the email list. Sagely Naturals is based in Santa Monica, California, and it only uses organic, non-GMO hemp. It tests each batch three times, and products are free from artificial colors, dyes, parabens, synthetic fragrances, and sulfates.


When testing this CBD pain relief rub, it was probably the most effective product, but it doesn't get the highest rating because of its additional ingredients. Though it does have that icy hot sensation which can be pretty intense, so it's likely the best option if you have a severe muscle injury.


What Are CBD Creams for Pain?

CBD creams for pain are topicals made with a number of all-natural ingredients, each of which is carefully chosen to help fight against inflammation and body aches. CBD creams are meant to be applied to targeted areas of the skin that are most affected by pain. While it takes CBD some time to penetrate the skin, once absorbed, it can begin to naturally relieve the targeted area.


CBD is a compound found in cannabis that has many health benefits without any psychoactive effects. In other words, it will not get you high but it will help you feel good because of its anti-inflammatory qualities, and it can provide ample pain relief without the danger associated with other painkillers.


CBD is just one of 85 chemical substances in the cannabis plant known as cannabinoids, and CBD pain relief creams are an excellent way to relieve pain while simultaneously nourishing your skin. The benefits of CBD range from anti-inflammatory to helping find optimal homeostasis.


Those with chronic pain can benefit from CBD pain relief creams because they can be applied directly to the source of the pain and the cream is quickly absorbed by the skin, providing instant relief without any psychoactive effects. Unlike other pain relief methods, CBD pain relief creams are safe and can be applied repeatedly as needed. In fact, these are some of the best ways to take CBD.


CBD pain relief creams are especially beneficial for the elderly, frail, or children with sore muscles or painful joints.


CBD lotions tend to come in three different extract types:


    • Full Spectrum - Contains all of hemp’s cannabinoids.
    • Broad Spectrum - Contains all of hemp’s cannabinoids except for tetrahydrocannabinol (THC).
    • Isolate - Purely CBD and no other cannabinoid.


Each extract type provides slightly different effects. Before purchasing a CBD cream, it’s important to familiarize yourself with these.


How to Use CBD Cream and Pain Relief Rubs

All of the products above will have instructions based on whether they are a topical cream or a salve. To begin, you'll want to store these away from heat, light, and humidity. For usage, apply to the affected area not more than three to four times daily. Rub the cream in thoroughly until it is absorbed. If you're newer to CBD, try smaller doses to start with and gradually work your way up.


What Are the Medical Benefits of CBD Creams?

While research is still limited, there has been evidence to suggest that CBD contains anti-inflammatory properties that can help reduce sensations of pain. These studies also suggest that CBD may be able to help with specific pain-related ailments, such as:


  • Arthritis - In a 2016 study, it was discovered that topical CBD relieved pain and swelling caused by arthritis in rats.
  • Jaw Pain - In a 2019 study, a group of individuals struggling with facial pains were requested to apply a CBD topical twice a day for two weeks. They reported feeling much less pain, specifically in the jaw region.
  • Nerve Pain - In a 2020 study, a group of people struggling with nerve damage used CBD topicals and found their pain levels reduced significantly.


Many people are turning to CBD for pain as it provides less risk of addiction in comparison to traditional painkillers.


Criteria for Choosing the Best CBD Creams for Pain

When deciding on the best CBD creams for pain, it was important for us to have strict criteria. Unfortunately, the CBD industry is currently unregulated, and with that, there are a number of companies out there simply trying to make a profit from this booming marketplace. When shopping for CBD online, it’s important to know what to look out for and how to ensure the products you’re receiving are safe and of the highest quality.


In order to do this, we made sure every company met the following requirements:


  • Certificate of Analysis (CoA) - One way brands help to ensure the safety and quality of their products is by running them through third-party lab tests. These tests provide unbiased results looking into a number of aspects of the CBD, including its cannabinoid and terpene count and whether or not it contains any contaminants such as heavy metals.
  • Extract Type - CBD products can be purchased in three different extract types. Each of these will have slightly different effects, and for that reason, you should familiarize yourself with them before purchasing a CBD product.
  • Hemp Source - Since hemp is highly absorbent, it can take in contamination from the soil it’s planted in. Because of this, it’s important to understand where the company is sourcing its hemp. We prefer companies that receive their hemp locally from an organic farm.
  • Ingredients - CBD creams are made from a number of ingredients. It’s important to look into these to ensure you don’t have any allergies to the product you’re purchasing. Not to mention, we prefer companies that use all-organic ingredients with no artificial additives.
  • Potency - The strength of a CBD product is always measured out in milligrams (mg). All reputable CBD brands will advertise the strength of the CBD somewhere on the label, and you can confirm this potency by taking a look at the product’s CoA. It’s important to understand how much hemp extract you’re receiving from a product as it will play a large role in how the product affects you.


Safety and Side Effects of CBD Creams

While CBD is often hailed as an all-natural remedy with no negative reactions, some people will experience mild cases of the following side effects:


  • Appetite changes
  • Diarrhea
  • Dry mouth
  • Drowsiness
  • Fatigue


It’s important to mention that if you are currently on prescription medication, you should consult your doctor before taking CBD creams for pain. While it’s fairly uncommon, CBD has occasionally been found to have negative interactions with certain medications.


If you are currently pregnant or lactating, you should avoid CBD altogether. At the moment, there just isn’t enough research to confirm that it’s safe for women of this category to consume CBD products.


Frequently Asked Questions

How long does CBD pain cream take to work?

CBD cream takes longer to work in comparison to other CBD consumption methods as cannabidiol needs more time to penetrate through the skin. While effects vary from person to person, most will feel something 15-30 minutes after application.

Where can you buy CBD cream for pain?

Our list above offers some insight into the best CBD creams for pain. Each of these can be purchased online and we offer coupon codes to help you save on your order. However, CBD creams can be purchased from a number of other online and in-store retailers too.


What is the best CBD cream for pain?

This is ultimately up to personal opinion. Going by our preferences, the above list suggests the best CBD creams for pain.


Who sells CBD cream for pain?

The majority of CBD companies on the market sell CBD cream for pain. However, before purchasing, we highly advise you to follow criteria similar to ours mentioned above.


Does CBD cream work for pain?

CBD cream has natural anti-inflammatory effects and therefore has the ability to relieve pain.

Top CBD Oil Companies

4 Reviews

  1. Lindsay

    Endoca should be at the top! Love their pain relief topical! 2019-06-08 05:23:59

  2. Chris

    I've tried the CBDol and agree with the review. The salve helped with my knee pain greatly! Stick to full-spectrum!! 2019-10-02 02:07:00

  3. Olivia

    I have been using Sagely CBD for awhile now and it's great on my knees and lower back. But it can get kind of expensive after awhile considering how much I use everyday trying to avoid taking ibuprofen. So I swap that out for Absorbine Jr. for when I am running low and in between my Sagely. It works amazing and lasts throughout my entire day and into my workouts. Plus it's super cheap and can be found anywhere. 2019-10-22 13:54:57

  4. daniellidman

    I have also tried CBD which i got from which has helped me for a while now with my chronic back pain and lower join pains and it works so tremendously and gives me good rest at night. In addition, it's supper affordable and cheap and it's everywhere. 2019-10-31 09:58:18

Drop your Review