Top 5 CBD Vape Pens
Best of 2023

Paul James Updated on December 30, 2022 Affiliate Disclosure Some links are specifically formatted for which we may receive a commission on resulting sales or clicks from affiliate partners (“Affiliate Links”).

CBD vape pens allow you to inhale CBD and provide you with an immediate reaction. But where do you buy CBD vape pens and which are the best on the market?

When it comes to cannabidiol (CBD) consumption, vaping is one of the most effective. This is thanks to the fact that it has an easier time entering your bloodstream through lung inhalation. In contrast, other popular products, like CBD oils and edibles, must be processed through your liver which requires additional time to metabolize.

For this reason, CBD vape pens have become popular among people with anxiety or those looking for immediate CBD relief. But with so many pens on the market, it can be difficult to determine which one is right for you. For this reason, we developed our list of the best CBD vape pens.

What are CBD Vape Pens?

CBD vape pens typically come in one of two varieties:

Disposable CBD Vape Pens – Vapes containing a battery, atomizer, and a pre-loaded cartridge that contains CBD e-juice. They work in a fashion very similar to e-cigarettes. Each disposable CBD vape pen usually comes preloaded with a few hundred puffs. Once the juice is depleted, the pen can be thrown out.

What are CBD Vape Pens?

Refillable CBD Vape Pens – A type of vape pen device that can be continually refilled with CBD e-juice, even after the first cartridge runs out. These usually require two purchases: 1.) a rechargeable battery (usually 510 thread) and 2.) either a pre-filled cartridge or tanks that can be refilled.


There’s no real difference between how these two CBD vape pens work. Both pens offer you the ability to take direct lung (DL) or mouth-to-lung (MTL) draws. With that said, both methods deliver their effects to your body in the same way.


However, the main difference between refillable and disposable pens is that a refillable CBD vape pen will typically have a longer lifespan and save you money in the long run. After purchasing a battery, CBD cartridges are relatively affordable. Not to mention, they come in more varieties – offering a more customizable experience.

On the other hand, the key benefit to a disposable vape pen is that there is no significant starting cost or commitment – if you find you don’t like CBD vaping, you’ve avoided investment in a long-term product.

Top 5 Best CBD Vape Pens

When it comes to conditions like anxiety, many self-report that CBD vape pens are extremely effective due to their immediate relief.

What Do CBD Vape Pens Do?

CBD vape pens will deliver similar effects to CBD oils, edibles, and other CBD products. The key difference is that you’re consuming your CBD through inhalation. This consumption method allows for CBD to enter through the lungs and into your bloodstream much quicker than other consumption methods out there.

In turn, vaping CBD delivers almost immediate effects. And many have turned to vape products for health conditions that require immediate relief. For example, some may find vaping CBD better for sudden anxiety attacks.

Are There Health Benefits to CBD Vape Pens?

At this moment, more research is required before the Food and Drug Administration (FDA) can approve CBD products for health benefits and medicinal use. However, there have been several self-reports of the therapeutic benefits CBD offers alongside some preliminary studies.

Some of these therapeutic effects include:


Using advanced brain imaging, research has shown that CBD can have an anxiolytic (anxiety-reducting) effect. Due to the way CBD can regulate mood, it’s being looked at as therapeutic treatment for depression, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD).

Epilepsy and Seizures

Presently, the only cannabis medication approved by the FDA is Epidiolex, which uses CBD to manage epilepsy and seizures. While research shows CBD’s ability to reduce or even block convulsions has dated back as far as 1970 – many are now finding the benefits themselves. For example, a young girl with Dravet syndrome named Charlotte Figi recently used CBD to drastically reduce her seizures. She reported a reduction in 1,200 monthly seizures to just 2 or 3.


CBD has been found to act as a natural anti-inflammatory and many have self-reported that it helps ward off various types of pain.


One of the few side effects that come with CBD is fatigue – especially when taken in higher doses. For this reason, CBD has been researched as a sleep-inducer. Not only have studies found that it can help with insomnia, but many have self-reported getting a better night’s rest after taking CBD.

Side Effects from Chemotherapy

While research has shown that CBD may inhibit cancer cell growth, there have been some notable studies showing it can help ease the side effects of chemotherapy, including nausea and vomiting.

CBD Vape Pens Dosage Recommendation

It is difficult to accurately track a CBD vape pen dosage as you never really know how many milligrams (mg) you’re getting with each puff. While some companies have taken the time to do the math, most will simply tell you how much CBD is included in the pen or cartridge.

If you’re new to vaping CBD and aren’t sure how much to inhale, we suggest starting small and working your way up. In other words, take 2 to 3 puffs and see how they make you feel. If you aren’t feeling the desired effects, work your way up to 5 or 6 puffs, then 8 to 10, and so on.

Like other medications and supplements, CBD has varying effects on different people. One of the biggest variables of these effects is your body weight. To give you a better idea of how CBD will affect you based on body weight, you can refer to our chart:

Body Weight Estimated CBD Dose
100 lbs 30mg
150 lbs 45mg
200 lbs 60mg
250 lbs 75mg

It’s also worth noting that you can develop a tolerance to CBD over time. For this reason, long-time CBD users may need to buy stronger products in order to feel the initial effects.

Furthermore, if you are currently taking any prescription medication, we strongly suggest that you consult your physician before taking CBD. While it is a rare occurrence, CBD has been found to negatively interact with certain medications.

Potential Side Effects and Concerns with CBD Vape Pens

When it comes to vaping products, there’s always been a concern surrounding the fact that you’re inhaling chemicals into your lungs. While studies have shown that vaping is typically safer than smoking, it’s too early to tell what the long-term consequences are.

Furthermore, the cannabis industry was recently under scrutiny when vaping products were sending people to hospitals, sometimes with fatal consequences. Fortunately for vape users, researchers have found the reason for the hospitalizations and adverse health effects was Vitamin E acetate – a naturally occurring compound that is found in the body and can also be extracted from certain foods. While Vitamin E is safe when consumed through digestion, it can be extremely dangerous when vaporized and inhaled.

The main reason for this outbreak was less reputable cannabis companies putting out products into the market that didn’t adhere to safety guidelines. In order to ensure the safety of our readers, we only included reputable CBD companies on this list. Furthermore, none of the products on this list contain Vitamin E acetate.


Beyond concerns specific to vaping, CBD can produce some undesirable side effects. While these are rare and typically only felt mildly, they remain a risk that users should be considered regardless of method of consumption:


  • Diarrhea
  • Drowsiness
  • Dry mouth
  • Fatigue
  • Reduced appetite


CBD Vaping Safety and Side Effects

Finally, if you’re pregnant or lactating, the FDA recommends caution when taking CBD as there aren’t enough long-term studies to show the effects of CBD on the health of the mother or children. If you are in this category, it may be safer to avoid CBD entirely.

How We Choose the Best CBD Vape Pens

In order to find the best CBD vape pens, we developed a criterium. If you plan on buying other CBD products not mentioned here, we recommend you have similar criteria:

Certificate of Analysis (CoA)

Since the CBD market is unregulated, it’s up to brands to ensure quality and safety for customers. An effective way of doing this is by running all batches of products through a third-party lab test.

The final lab report of these tests is called a Certificate of Analysis (CoA). By reading a brand’s CoA, you can get an idea of the cannabinoid profile and whether or not a product contains contaminants, such as heavy metals and pesticides.

Customer Reviews

If you’re wondering how a CBD vape pen is going to make you feel, your best bet is to read the customer reviews. These are first-hand experiences that can give you insight into how a particular product made other people feel. All the vape pens on our list have positive customer reviews.


The e-liquid used in a CBD vape pen is typically made from propylene glycol (PG) and vegetable glycerin (VG). These ingredients are considered safer to consume than traditional smoke – though, long-term impacts still need to be studied.

All of the vape pens on our list incorporate PG and VG along with a CBD extract. Furthermore, some include other active ingredients, such as melatonin. Finally, you’ll also find some flavoring within a CBD vape pen.

Before purchasing, we highly recommend checking out the ingredients list to ensure vape pens meet your dietary restrictions. If you struggle with a lung condition, such as asthma, it’s best to avoid CBD vape pens altogether.

Extract Type

CBD vape pens can be purchased in three different extract types. These are:

  • Full-spectrum – Contains all of the beneficial cannabinoids and phytonutrients found in the hemp plant.
  • Broad-Spectrum – Exact same as full-spectrum, except the THC is removed.
  • Isolate – The purest form of CBD, usually over 99%.

Our list covers full-spectrum and broad-spectrum extract types. Unfortunately, we could not find a reputable CBD isolate pen on the market. Still, there are CBD isolate e-juice and cartridge options for those interested.


CBD vape pens have their potencies measured out in milligrams (mg). The higher this number, the stronger a product is. In order to create a diverse list, we included a variety of different potencies.

Paul James

Paul James is a seasoned cannabis and CBD writer and expert. He is a mental health blogger who advocates CBD as a natural alternative to prescription medications. You can read more about this and other natural alternatives on his blog:"


While we’ve provided 8 suggestions for the best CBD vape pens currently on the market, you can purchase similar products just about anywhere – whether online or at a local smoke shop. However, considering the concerns many have with cannabis-related vape pens, we recommend you follow our criteria when looking for the right CBD vape pens.