Top 8 CBD Vape Pens
Best of 2022

Paul James Updated on February 10, 2022 Affiliate Disclosure Some links are specifically formatted for which we may receive a commission on resulting sales or clicks from affiliate partners (“Affiliate Links”).

CBD vaping products have become increasingly popular. But where do you begin? Here are our top picks for the best CBD vape pens of 2021.

If you’re new to cannabidiol (CBD), you’re going to find that there are a number of consumption methods to get you started. These include CBD oil, CBD coffee, CBD capsules, and others. One of the most popular ways to consume CBD is vaping and it’s considered one of the most effective and quickest-acting methods currently out there.

CBD vaping is quick-acting because it’s easier for cannabidiol to enter our bloodstream through our lungs when inhaling. In contrast, other popular products, like CBD oils and edibles, must be processed through your liver which requires additional time to metabolize. Therefore, it takes longer to feel the effects of cannabinoids and terpenes.

What are CBD Vape Pens?

CBD vape pens typically come in one of two varieties:

  • Disposable CBD Vape Pens – vapes containing a battery, atomizer, and a pre-loaded cartridge that contains CBD e-juice. They work in a fashion very similar to e-cigarettes. Each disposable CBD vape pen usually comes preloaded with a few hundred puffs. Once the juice is depleted, the pen can be thrown out.
  • Refillable CBD Vape Pens – a type of vape pen device that can be continually refilled with CBD e-juice, even after the first cartridge runs out. These usually require two purchases: 1.) a rechargeable battery (usually 510 thread) and 2.) either a pre-filled cartridge or tanks that can be refilled.


It’s easier for cannabidiol to enter our bloodstream through our lungs when inhaling

There’s no real difference between how these two CBD vape pens work. Both pens offer you the ability to take direct lung (DL) or mouth-to-lung (MTL) draws. With that said, both methods deliver their effects to your body in the same way.


However, the main difference between refillable and disposable pens is that a refillable CBD vape pen will typically have a longer lifespan and save you money in the long run. After purchasing a battery, CBD cartridges are relatively affordable.

On the other hand, the key benefit to a disposable vape pen is that there is no significant starting cost or commitment – if you find you don’t like CBD vaping, you’ve avoided investment in a long-term product.

When it comes to conditions like anxiety, many self-report that CBD vape pens are extremely effective due to their immediate relief.

What Do CBD Vape Pens Do?

CBD vape pens will deliver similar effects to CBD oils, edibles, and other CBD products. The key difference is that you’re consuming your CBD through inhalation. This consumption method allows for CBD to enter through the lungs and into your bloodstream much quicker than other consumption methods out there.

Since vaping CBD delivers almost immediate effects, many have turned to vape products for ailments that require immediate relief. For example, some may find vaping CBD better for sudden anxiety attacks.

Are There Health Benefits to CBD Vape Pens?

At this moment, more research is required before the Food and Drug Administration (FDA) can approve CBD products for health benefits and medicinal use. However, there have been several self-reports of the therapeutic benefits CBD in itself offers alongside some preliminary studies.

Some of these therapeutic effects include:

  • Anxiety – Using advanced brain imaging, research has shown that CBD can have an anxiolytic (anxiety-reducting) effect. Due to the way CBD can regulate mood, it’s being looked at as therapeutic treatment for depression, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD).
  • Epilepsy and Seizures – Presently, the only cannabis medication approved by the FDA is Epidiolex which uses CBD to manage epilepsy and seizures. While research shows CBD’s ability to reduce or even block convulsions has dated back as far as 1970 – many are now finding the benefits themselves. For example, a young girl with Dravet syndrome named Charlotte Figi recently used CBD to drastically reduce her seizures. She reported a reduction in 1,200 monthly seizures to just 2 or 3.
  • Inflammation – CBD has been found to act as a natural anti-inflammatory and many have self-reported that it helps ward off various types of pain.
  • Insomnia – One of the few side effects that come with CBD is fatigue – especially when taken in higher doses. For this reason, CBD has been researched as a sleep-inducer. Not only have studies found that it can help with insomnia, but many have self-reported getting a better night’s rest after taking CBD.
  • Side Effects from Chemotherapy – While research has shown that CBD can inhibit cancer cell growth, there have been some notable studies showing it can help ease side effects of chemotherapy, including nausea and vomiting.


It’s important to also point out that these health benefits may appear from any CBD consumption methods and aren’t exclusive to CBD vaping. The main reason you may choose a vape product over a tincture or CBD gummy is if you’re looking for immediate effects.

CBD Vape Pens Dosage Recommendation

It is difficult to accurately track a CBD vape pen dosage as you never really know how many milligrams (mg) you’re getting with each puff. While some companies have taken the time to do the math, most will simply tell you how much CBD is included in the pen or cartridge.

If you’re new to vaping CBD and aren’t sure how much to inhale, we suggest starting small and working your way up. In other words, take 2 to 3 puffs and see how they make you feel. If you aren’t feeling the desired effects, work your way up to 5 or 6 puffs, then 8 to 10, and so on.

Like other medications and supplements, CBD has different effects on different people. Some of the variables that may impact how CBD affects you include:

  • Ailment – If you’re taking CBD for a specific reason (i.e. anxiety or inflammation), consider how strong your ailment is in comparison to others. The stronger the ailment, the more CBD you may need.
  • Body Weight – Generally speaking, the more you weigh, the more CBD you’ll need in order to feel the effects.
  • Strength – Every CBD product has its potency measured out in milligrams (mg). The higher this number, the stronger a product is. The stronger a product is, the less inhaling you need to do in order to feel the effects.
  • Tolerance – Our bodies naturally develop a tolerance to CBD over time. Therefore, if you’ve been taking CBD for a while, you may need to consume more of it in order to achieve the same effects you experienced the first time.


If you are currently taking any prescription medication, we strongly suggest that you consult your physician before taking CBD. While it is a rare occurrence, CBD has been found to negatively interact with certain medications.

Our Criteria for the Best CBD Oil

Since the CBD industry is unregulated by the FDA, it’s important to make sure that you’re purchasing high-quality products. When deciding on top CBD companies and the best quality CBD oil, we established a set of criteria to evaluate these products on. These criteria include:

  • Certificate of Analysis – A reputable CBD brand greatly values and tries to ensure the quality of its product and the safety of its customers. One way they do this is by running CBD production batches through a 3rd-party lab test. These tests measure the exact makeup of the product, including the percentages of phytocannabinoids you’ll be consuming. At the same time, they’ll also test for contaminants, such as heavy metals and pesticides. We recommend that the CBD brand you purchase from offers access to these lab reports.
  • Hemp Source – CBD comes from the hemp plant. Therefore, it’s vital that the plant itself was grown organically and locally sourced. All brands on our list are involved with their hemp production and CBD products from seed to sale.
  • Ingredients – CBD oils are typically only made using three ingredients: a carrier oil (usually MCT coconut oil or hemp seed oil), hemp extract, and flavoring. It’s important to ensure that these ingredients meet your dietary specifications, that you aren’t allergic to any of the ingredients, and that they’re all-natural.
  • Extract Type – As mentioned, CBD comes in three different extract types: full-spectrum, broad-spectrum, and isolate. To develop a well-rounded list, we made sure to give you a variety of each.
  • Potency – We prefer companies that offer a wide range of potencies. These can be viewed through the milligram (mg) count labeled on the CBD product. We made sure to source CBD brands that offered their oils in potencies that are viable for both new users as well as long-time CBD users.
  • Pricing – While the price of a CBD oil shouldn’t be a deciding factor of whether you choose to buy a certain product or not, it can give you some insights as to the quality of the CBD. Admittedly, more expensive products tend to be safer and more potent, typically because of higher quality ingredients and advanced manufacturing processes.

Potential Side Effects and Concerns with CBD Vape Pens

When it comes to vaping products, there’s always been a concern surrounding the fact that you’re inhaling chemicals into your lungs. While studies have shown that vaping is typically safer than smoking, it’s too early to tell what the long-term consequences of vaping CBD could be.

Furthermore, the cannabis industry was recently under scrutiny when vaping products were allegedly sending people to hospitals, sometimes with fatal consequences. Fortunately for vape users, researchers have found the reason for the hospitalizations and adverse health effects were Vitamin E acetate – a naturally occurring compound that is found in the body and that can also be extracted from certain foods. While Vitamin E is safe when consumed through digestion, it can be extremely dangerous when vaporized and inhaled.

The main reason for this outbreak was less reputable cannabis companies putting out products into the market that didn’t adhere to safety guidelines. In order to ensure the safety of our readers, we only included reputable CBD companies on this list. Furthermore, none of the products on this list contain Vitamin E acetate.

Beyond concerns specific to vaping, CBD can produce some undesirable side effects. While these are rare and typically only felt mildly, they remain a risk that users should be considered regardless of method of consumption:

  • Diarrhea
  • Drowsiness
  • Dry mouth
  • Fatigue
  • Reduced appetite


Finally, if you’re pregnant or lactating, the FDA recommends caution when taking CBD as there aren’t enough long-term studies to show the effects of CBD on the health of the mother or children. If you are in this category, it may be safer to avoid CBD entirely.

Paul James

Paul James is a seasoned cannabis and CBD writer and expert. He is a mental health blogger who advocates CBD as a natural alternative to prescription medications. You can read more about this and other natural alternatives on his blog:"


While we’ve provided 8 suggestions for the best CBD vape pens currently on the market, you can purchase similar products just about anywhere – whether online or at a local smoke shop. However, considering the concerns many have with cannabis-related vape pens, we recommend you follow our criteria when looking for the right CBD vape pens.