Cannabinol (CBN) Introductory Guide Most people have heard of cannabidiol (CBD) and tetrahydrocannabinol (THC). They’re the two most abundant cannabinoids in cannabis and play a major role in its effects.   But they’re not alone. Cannabis contains many other minor cannabinoids, including cannabinol (CBN). Despite being the first cannabinoid to be isolated from the plant in 1896, CBN hasn’t received much attention.1   That’s because most minor cannabinoids are present in only trace amounts. Some people recognize CBN as the compound that makes old weed more sedating, but there’s a lot more to it.   And many are starting to realize this. You may have seen CBN products hit the market recently. So, what is CBN oil and what can it be used for? We invite you to follow along as we take a deeper look.   What is Cannabinol (CBN)? CBN is one of more than 120 different active components, or cannabinoids, found in the cannabis plant.2   THC breaks down into CBN over time, especially when exposed to oxygen.3 This is why CBN concentrations are very small in raw cannabis but can reach significant levels in older, dried plants.   Most of the cannabinoids in cannabis are considered “minor” because their concentrations are quite small — less than 1%. CBN is one such cannabinoid.   Like CBD, CBN is completely non-intoxicating, so it can’t get you high. Interest in CBN has been steadily growing because it appears to have a wide variety of potential health benefits.   Some people even consider CBN and other minor cannabinoids to be the “next big thing” following in the footsteps of CBD’s success.   Is Cannabinol Legal? Yes, as long as CBN is derived from hemp, it’s completely legal. Hemp is one of the two main kinds of cannabis, the other being marijuana. By definition, marijuana has significant THC levels, whereas hemp contains 0.3% or less of this intoxicating cannabinoid.   The 2018 Farm Bill made hemp an agricultural commodity in the United States, which means that any cannabinoid product sourced from it is also legal. CBN extracted from any type of cannabis is also legal in Canada.   As for the rest of the world, the legality of CBN can vary. Some countries ban cannabis (including hemp) completely, which means any part or extract of the plant — including CBN — is illegal.   Meanwhile, in other places where hemp is legal, CBD, CBN, and any other cannabinoid derived from hemp are also legal.   However, because hemp plants have low THC levels and CBN comes from the breakdown of THC, it can be difficult and expensive to make CBN products from hemp.   As such, most CBN products are sourced from marijuana and only sold in states and countries where it’s legal.   How Does Cannabinol Work? Like most cannabinoids, CBN seems to work by interacting with your endocannabinoid system (ECS). This system regulates all major bodily processes, including brain function, metabolism, and sleep, to maintain homeostasis — a healthy state of balance.   The ECS is composed of three major parts: 4   Endocannabinoids — cannabinoids produced on-demand by your body.   Enzymes that help build and break down endocannabinoids.   Cannabinoid receptors are found in all parts of the body. The CB1 receptor is especially common in the brain and the CB2 receptor in immune system cells.5   Cannabinoid receptors can be activated by both “endo” (naturally produced in the body) and “phyto” (plant-derived) cannabinoids. For example, the phytocannabinoid THC produces most of its effects by binding CB1.6   As for CBN, research suggests that it has a lower attraction to CB1 receptors than THC, but a higher one for CB2 receptors, which means it might have stronger effects on the immune rather than the nervous system.7   Still, we don’t know enough about how CBN works because most minor cannabinoids are not well-researched. It’s quite possible that it may affect other parts of the body aside from the ECS, similar to CBD.   CBN also contributes to the “entourage effect” — the proposed synergy between cannabinoids and other active components of cannabis, which strengthen their overall effects.8   This effect means that using whole-plant cannabis is better than isolated compounds, such as CBD or CBN on their own.   The entourage effect has been demonstrated by multiple studies. In the case of CBN, for example, studies in rabbits and rats have shown that it can synergize with THC, enhancing its sedating and intoxicating effects.9   However, more research is needed to explain exactly how CBN works, what it may be able to treat, and how it contributes to the entourage effect.   Where to Buy CBN Oil? CBN can come in many product forms. For now, CBN oil is the most common but cannabinol can theoretically be offered in all of the same product types as CBD, including capsules, isolates, edibles, topicals, and vape products.   Just like CBD products, the best place to buy CBN is online. They’re just starting to appear because most legal cannabis products are made from hemp, which has naturally lower CBN and THC levels.   CBN can come in several formulations. The simplest one is isolate: pure cannabinol and nothing else.   You can also find whole-plant CBN preparations. These typically combine full-spectrum hemp extract with CBN isolate to create a product that has high CBD and CBN levels and maintains all of the other cannabinoids found in hemp.   This type of product shouldn’t be confused with a regular full-spectrum CBD extract. Standard full-spectrum CBD can contain CBN but only in very small amounts.   Similarly, you might also be able to find broad-spectrum CBN products, which are the same as full-spectrum formulations but with zero THC.   Whole-plant hemp products also contain many other natural substances, including terpenes — aromatic molecules responsible for the characteristic aromas and flavors of plants, including various cannabis strains.10   Terpenes play a notable role in the entourage effect by not only providing beneficial effects of their own but also working in synergy with cannabinoids. For example, terpenes can enhance the passage of cannabinoids across the blood-brain barrier, enhancing their efficacy.11   Finally, some products combine CBN isolate with CBD isolate for a 1:1 formula.   Cannabinol Effects There are few studies of CBN and most of the research is restricted to investigations in animals. So far, all we know is that CBN can enhance the sedating and intoxicating effects of THC and may have other beneficial properties, such as suppressing appetite. With this, some researchers suggest it may be able to be used as a sleep aid or to alleviate anxiety.   But we don’t know much about its potential side effects and drug interactions, especially after prolonged use.   Cannabinol Dosage The right amount of CBN to take is different for everyone. That’s because the optimal dosage of any cannabinoid is influenced by many factors, such as your body weight, genetics, and medical symptoms.   Additionally, CBN and other cannabinoid products can come in various formulations, concentrations, and consumption methods, which will further affect your dosage.   For example, cannabinoids are known to have poor oral absorption,12 so you’ll need to take higher doses of an oral CBN product (such as capsules) to achieve the same effects as a sublingual oil.   As for actual amounts, there’s very little research data for CBN dosages. However, one good starting point is the doses used for CBD, which is another non-intoxicating cannabinoid with similar effects. Most people take about 10-50 mg of CBD once or twice daily.   Using this information, you can start with a CBN dose of about 10-15 mg and see how it makes you feel. If there’s no effect, you can gradually raise the dosage over time until you start noticing the desired benefits.   Choosing the Right Type of CBN Extract You also have to consider what type of CBN formulation you want to use. If you want nothing but pure CBN, you should look for products containing isolate.   Meanwhile, if you want to benefit from the entourage effect, you should look for a full-spectrum cannabis formulation.13   In most cases, this will be a standard whole-plant CBD extract that’s been enriched with CBN, so it will contain all of the cannabinoids, terpenes, and other potentially beneficial hemp phytochemicals.   Finally, if you want to maximize the benefits of hemp but avoid ingesting THC, you should look for a broad-spectrum CBN formulation. These products will have all of the same ingredients as a full-spectrum extract but undergo an additional step to remove THC.   CBN Benefits and Health Conditions CBN has been examined in multiple scientific studies. As with other cannabinoids, the research suggests that CBN may have multiple health applications. Here’s an overview of the key findings:   CBN may have anti-inflammatory properties.14 CBN may have antibacterial effects.15 CBN may have anticonvulsant effects that can help with seizures, although it’s weaker than CBD and THC.16 CBN may have neuroprotective qualities. In one study, cannabinol delayed the development of the neurodegenerative condition amyotrophic lateral sclerosis (ALS) in mice.17 CBN may have appetite-stimulating properties. In one animal study, it significantly increased the food intake of mice.18 CBN may have analgesic effects; it reduced muscle pain in a rat study.19   Having said that, CBN is a relatively under-researched cannabinoid and most of these effects have not yet been studied in humans. But we can expect more findings in the years to come, especially as the interest in minor cannabinoids continues to grow.   Does CBN Help with Sleep? There’s a popular belief that CBN has a potent sedative or sleep-promoting effects. Unfortunately, this is a misconception based on the observation that old, dried cannabis — which has higher CBN concentrations — seems to make people more sleepy.   While it is true that CBN is higher in aged cannabis, it’s not necessarily the compound responsible for its notable sedative effects.   For one, dried, old cannabis tends to contain higher levels of sedating, oxygenated sesquiterpenes, compounds closely related to terpenes.20 Also, CBN may be able to enhance the sedating effects of other cannabinoids.   This was demonstrated by an older study where the researchers gave people pure THC, CBN, or both. CBN did not make people sleepy or high on its own.   However, when the study participants took both cannabinoids together, they reported feeling more drugged, drunk, dizzy, and drowsy compared to THC alone.21 This is also a great example of CBN’s role in the entourage effect.   Frequently Asked Questions What is CBN oil good for? We don’t know enough about the effects of CBN oil to say what it might be good for. However, it may work well for aiding sleep if it contains significant amounts of THC or other cannabinoids with sedative properties.   What is the difference between CBD and CBN oil? The key difference is in the amount of CBN. CBD oil might contain low levels of CBN, whereas a proper CBN oil will have high concentrations of CBN, typically about as much or more than CBD.   What are the effects of CBN? So far researchers have found that CBN may have anti-inflammatory, pain-relieving, antibacterial, neuroprotective, anticonvulsant, and appetite-stimulating effects. But these have not yet been confirmed in human studies. It also seems to enhance the intoxicating and sedating effects of THC.   Which is better for sleep CBD or CBN? It’s far too early to say because there isn’t any significant research evidence backing either cannabinoid. Anecdotally, many people have found that CBD can help them sleep. Similarly, some have reported getting better sleep after taking CBN, especially when it’s combined with THC and other cannabinoids.   References 1.  Hanuš, Lumír Ond?ej, et al. "Phytocannabinoids: a unified critical inventory." Natural product reports 33.12 (2016): 1357-1392.   2.  Morales, Paula, Dow P. Hurst, and Patricia H. Reggio. "Molecular targets of the phytocannabinoids: a complex picture." Phytocannabinoids. Springer, Cham, 2017. 103-131.   3.  Brenneisen, Rudolf. "Chemistry and analysis of phytocannabinoids and other Cannabis constituents." Marijuana and the Cannabinoids. Humana Press, 2007. 17-49.   4.  Lu, Hui-Chen, and Ken Mackie. "An introduction to the endogenous cannabinoid system." Biological psychiatry 79.7 (2016): 516-525.   5.  Turcotte, Caroline, et al. "The CB 2 receptor and its role as a regulator of inflammation." Cellular and Molecular Life Sciences 73.23 (2016): 4449-4470.   6.  Hua, Tian, et al. "Crystal structure of the human cannabinoid receptor CB1." Cell 167.3 (2016): 750-762.   7.  Andre, Christelle M., Jean-Francois Hausman, and Gea Guerriero. "Cannabis sativa: the plant of the thousand and one molecules." Frontiers in plant science 7 (2016): 19.   8.  Russo, Ethan B. "The case for the entourage effect and conventional breeding of clinical cannabis: no “strain,” no gain." Frontiers in plant science 9 (2019): 1969.   9.  Takahashi, R. N., and I. G. Karniol. "Pharmacological interaction between cannabinol and D9-tetrahydrocannabinol." Psychopharmacologia (1975).   10.  Cox-Georgian, Destinney, et al. "Therapeutic and medicinal uses of terpenes." Medicinal Plants. Springer, Cham, 2019. 333-359.   11.  Hartsel, Joshua A., et al. "Cannabis sativa and Hemp." Nutraceuticals. Academic Press, 2016. 735-754.   12.  Bruni, Natascia, et al. "Cannabinoid delivery systems for pain and inflammation treatment." Molecules 23.10 (2018): 2478.   13.  Maayah, Zaid H., et al. "The anti-inflammatory and analgesic effects of formulated full-spectrum cannabis extract in the treatment of neuropathic pain associated with multiple sclerosis." Inflammation Research (2020): 1-10.   14.  Zurier, Robert B., and Sumner H. Burstein. "Cannabinoids, inflammation, and fibrosis." The FASEB Journal 30.11 (2016): 3682-3689.   15.  Appendino, Giovanni, et al. "Antibacterial cannabinoids from Cannabis sativa: a structure− activity study." Journal of natural products 71.8 (2008): 1427-1430.   16.  Karler, Ralph, William Cely, and Stuart A. Turkanis. "The anticonvulsant activity of cannabidiol and cannabinol." Life Sciences 13.11 (1973): 1527-1531.   17.  Weydt, Patrick, et al. "Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival." Amyotrophic Lateral Sclerosis 6.3 (2005): 182-184.   18.  Farrimond, Jonathan A., Benjamin J. Whalley, and Claire M. Williams. "Cannabinol and cannabidiol exert opposing effects on rat feeding patterns." Psychopharmacology 223.1 (2012): 117-129.   19.  Wong, Hayes, and Brian E. Cairns. "Cannabidiol, cannabinol and their combinations act as peripheral analgesics in a rat model of myofascial pain." Archives of oral biology 104 (2019): 33-39.   20. Russo, Ethan B. “Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.” British Journal of Pharmacology 163 (2011): 1244-1364.   21.  Karniol, Isac G., et al. "Effects of Δ9-tetrahydrocannabinol and cannabinol in man." Pharmacology 13.6 (1975): 502-512.

CBD Reduces Lung Inflammation in Respiratory Illnesses Like COVID-19, Pneumonia, and More Recent research has highlighted a potential role for CBD in reducing lung damage caused by acute respiratory distress syndrome (ARDS) – a common condition seen in patients with COVID-19, lung infections, severe pneumonia, and other respiratory diseases or injuries.   Cannabidiol (CBD) is one of over a hundred naturally occurring compounds found in hemp and cannabis. But unlike other cannabinoids such as THC, CBD is completely non-intoxicating.   It has long been suggested that CBD can have anti-inflammatory properties due to the molecules’ ability to interact with the human endocannabinoid system – a signaling network between cells that can control immune responses.    Recent studies in animals have confirmed that CBD can be used to treat excessive lung inflammation seen in ARDS and other respiratory illnesses.   Studies Suggest CBD can Reduce ARDS-Associated Lung Damage Early research from the Medical College of Georgia at Augusta University has recently shown that pure CBD can help lungs recover from ARDS and restore healthy oxygen levels.   “ARDS is a major killer in severe cases of some respiratory viral infections, including [COVID-19],” said immunologist and study author Babak Baban. “We have an urgent need for better intervention and treatment strategies.”   ARDS trigger what researchers call a “cytokine storm.” Cytokines are important molecules secreted by immune cells to communicate and coordinate recovery efforts.   However, in ARDS there is an overproduction of these cytokines, creating a dangerous overactive immune response. In the confusion, immune cells can begin inadvertently attacking the lungs, furthering the damage.   No cure is currently available for ARDS, and most patients with ARDS will require ventilator support. Mechanical ventilators can take over the breathing functions for the patient, giving the lungs a chance to recover from the infection.   However, studies suggest that even with ventilators, approximately 27% of patients with ARDS will die, with the risk of death increases with age and severity of illness.   In their studies, the research team triggered ARDS in mice using three doses of foreign RNA molecules similar to those found in respiratory viruses such as COVID-19.   Afterward, some mice were given a CBD treatment shot in the abdomen every other day for a total of three days. The timeline was specifically designed to mimic a human patient seeking medical care after experiencing troubled breathing.   In mice administered pure CBD, oxygen levels went up and temperatures and cytokine levels went down over time. Additional analysis of the lung tissues further showed that CBD significantly prevented physical lung damage such as scarring and swelling.   The finding suggests that CBD can quell the overactive immune response seen in ARDS.   However, if CBD is given too early, co-author and physician-scientist Dr. Jack Yu said it may interfere with the body’s healthy immune response.   A second study by the research team has further shown that one way CBD appears to reduce ARDS-associated lung damage is through increasing the anti-inflammatory molecule, apelin.   Apelin levels decrease during viral infection, but “CBD almost brought it back to a normal level,” Yu said.   Because of the association, the team suggests that low apelin levels could be an early indicator of ARDS, however, whether CBD protects the lungs through other mechanisms as well will require additional studies.   Synthetic CBD for COVID-19 Currently in Phase-1 Clinical Trial The growing research interest surrounding the use of CBD to treat ARDS has led to the development of a synthetic CBD-based drug, ARDS-003, which has been granted FDA approval to begin phase-1 clinical trials.   The drug is under development by Tetra-Bio-Pharma, a pharmaceutical company focused on cannabinoid-derived drug development.   Unlike pure CBD, which is purified from the cannabis plant, ARDS-003 is synthetically derived but can interact with the same immune signaling network CBD does – the human endocannabinoid system.   “We have extensive preclinical evidence that the active pharmaceutical ingredient in ARDS-003 has a profound effect in inhibiting factors that lead to excessive immune system activation,” Tetra Bio-Pharma CEO Guy Chamberland told Forbes.   The randomized, double-blind, placebo-controlled clinical study is scheduled to begin enrollment in December 2020. If successful, the company plans to begin phase 2 studies in the second quarter of 2021.   CBD May Also Prevent Lung Damage in Other Respiratory Diseases While most research on the use of CBD is currently centered around COVID-19, ARDS can be seen in a variety of respiratory illnesses such as influenza, pneumonia, sepsis, and other physical lung and chest injuries.   A Brazilian research team has found that CBD can improve lung function and inflammation in mice with acute lung injuries.   CBD has also been shown to reduce airway inflammation in mice with allergic asthma, the most common type of asthma that can be triggered through allergens such as pollen, dust, and smoke.   Considering the positive effects observed with CBD thus far and the importance of the endocannabinoid system in the human body, Baban’s research team said in their study that “it is plausible CBD may be used as a therapeutic candidate in the treatment of various inflammatory conditions.”

Best CBD Lubes ‌‌|‌‌ November 2020 When people first hear about cannabidiol (CBD) lube, it tends to raise a lot of confusion. These are unusual products, we admit. However, these are also some highly effective products that may change the way you look at sex. And in order to have this perspective change, it is important that you know where to find and purchase the best CBD lubes.   Due to CBD’s ability to help keep the endocannabinoid system (ECS) in an optimally-balanced physical state, it is able to produce a variety of potential medical benefits. Many of these benefits stream down to genital issues some may have - from menstrual cramps to dryness to even difficulty achieving arousal.   For these reasons, the market for CBD lube has been rapidly growing lately. And as this market continues to expand, more and more brands are coming out with their lubricants. In order to identify which are the best CBD lubes on the market, we put together our own list. We invite you to follow along!   Top Ranking CBD Lubes 1.) Foria Wellness Rating 5/ 5 Extract Type: Broad-spectrum Total CBD Range: 200mg Potency Range: 1.66mg per mL Price Range: $44.00 Value ($/mg): $0.22 per mg THC Content: 0.0% Lab Report: See Here Scent Variations: 1 Potency Variations: 1   Foria Wellness Pros: Foria Wellness specializes in developing intimacy CBD products Only uses two ingredients - MCT coconut oil and organic hemp extract Offers a subscription service to help you save   Foria Wellness Cons: Relatively pricier than other CBD lubricants on our list   Foria Wellness has developed a reputation for crafting some of the highest-quality CBD intimacy products on the market, and their Intimacy Natural Lubricant with CBD is no exception!   Each 4-ounce bottle comes with 200mg of broad-spectrum CBD - offering you all the beneficial cannabinoids found in the hemp plant with the exception of THC. Other than that, this lubricant only uses organic MCT coconut oil as a carrier.   Many Foria Wellness customers have reported that this lubricant was able to help with a number of different issues: from vaginismus to pelvic/genital pain to relief of some menopause complications. However, the biggest claim Foria Wellness fans make is that this lubricant is a game-changer when it comes to intimacy and can be a real orgasm enhancer.   Each bottle costs $44 which is a bit pricier than other products on our list. However, after you use this product once, you will know that your money was well spent.   2.) Privy Peach Rating 4.5/ 5 Extract Type: Broad-spectrum Total CBD Range: 180mg - 360mg Potency Range: 3mg - 8.33mg per mL Price Range: $45.00 - $60.00 Value ($/mg): $0.15 - $0.26 per mg THC Content: 0.0% Lab Report: On individual product pages Scent Variations: 3 Potency Variations: 3   Privy Peach Pros: Comes in 3 different formulas Made using vegan ingredients - products are cruelty-free Lubes are individually-packed for a more convenient serving size   Privy Peach Cons: These products can degrade latex   Privy Peach is the only company on our list that offers three different types of CBD lubes. These can be found in their “Between the Sheets” shopping category which hosts other intimate CBD products.   CBD Lube (Intimate Oil) - Privy Peach’s standard CBD lube is designed to promote arousal and ease sexual discomfort. It comes with 300mg of broad-spectrum CBD extract.   Coco Jambo-Exploratory Anal CBD Lubricant - With 360mg total CBD, Privy Peach’s anal lubricant has a thicker formula specifically designed for exploratory play.   Erotic Oil - Sensation Intensifying Intimate Oil - With 180mg total CBD, this CBD lubricant enhances sexual arousal by using a number of all-natural ingredients, including cocoa butter, jasmine, lavender, peppermint, and cardamom.   Pricing on these CBD lubricants varies depending on the product of your choice. While the specialty products tend to cost more, they are masterfully crafted for specific sexual activities and we believe the extra money is well worth it.   3.) Infinite CBD Rating 4/ 5 Extract Type: Isolate Total CBD Range: 150mg Potency Range: 2.5mg per mL Price Range: $24.50 Value ($/mg): $0.16 per mg THC Content: 0.0% Lab Report: On individual product pages Scent Variations: 1 Potency Variations: 1   Infinite CBD Pros: Can be used as a lubricant or as a massage oil Made with all-natural ingredients, including essential oils Made from organic hemp grown in Colorado, USA   Infinite CBD Cons: Uses CBD isolate - no entourage effect   Infinite CBD’s lubricant - appropriately called “Big Bang” - is more than just another CBD lube. Using a variety of essential oils - from vanilla to ylang-ylang to clary sage - Infinite CBD has developed a topical that offers a unique experience.   Each bottle comes with 150mg of CBD isolate which means this CBD lube contains pure cannabidiol and no other cannabinoid. With that, you get 2.5mg per milliliter (an estimated 0.5mg per pump). In terms of CBD-count, this is a fairly low amount. However, thanks to the other all-natural ingredients involved here, we are certain that this lubricant will help you feel better in several ways.   Infinite CBD also advertises that their CBD lubricant can also be used as massage oil which can be great for those back rubs to help with back pain. Each bottle costs $24.50 and you can use our Infinite CBD coupon code to help you save on your order.   4.) Ananda Hemp Rating 4/ 5 Extract Type: Full-Spectrum Total CBD Range: 250mg Potency Range: 4.16mg per mL Price Range: $46.00 Value ($/mg): $0.18 per mg THC Content: <0.3% Lab Report: On individual product pages Scent Variations: 1 Potency Variations: 1   Ananda Hemp Pros: Made using organic hemp and a number of essential oils Uses a full-spectrum blend of cannabinoids and synergistic terpene infusion Only produces this lubricant in small batches to ensure quality   Ananda Hemp Cons: Some reviews claim the lubricant does not last long enough   Ananda Hemp’s Bliss Intimate Oil is another popular CBD lubricant on the market, and for good reason. By using a full-spectrum blend of hemp’s cannabinoids along with synergistic terpene infusion, this lube is bound to ease tension and increase pleasure.   Furthermore, Ananda Hemp has crafted this oil using a number of essential oils, including black pepper, peppermint, and coconut. Beyond providing a delightful aurora, these ingredients were carefully chosen to help promote sexual arousal and to help decrease any discomfort you may have down there.   Each bottle costs $46 and comes with 250mg of full-spectrum CBD. While the initial price may seem a bit expensive, this is a fairly good deal when considering the price per milligram (mg).   5.) GoLove CBD Rating 4/ 5 Extract Type: Isolate Total CBD Range: 25mg - 200mg Potency Range: 5mg per mL Price Range: $5.00 - $68.00 Value ($/mg): $0.20 - $0.34 per mg THC Content: 0.0% Lab Report: See Here Scent Variations: 1 Potency Variations: 1   GoLove CBD Pros: Company solely focuses on CBD lube and no other CBD product Offers sample packets for only $5 for those interested in trying the product Lubricants are dermatologist-tested   GoLove CBD Cons: The 200mg (40mL) lubricant is actually more expensive than the sample packet (on a per mg basis)   If you’re looking for a brand that wants you to make the most out of your CBD lubricant experience, look no further than GoLove CBD. Their sole focus in the cannabidiol space is CBD lubricant and, with that, they have designed one of the highest quality lubes currently on the market.   Each oil can be purchased in a sample pack (25mg total) for $5 or a standard bottle (200mg total) for $68. These lubricants are water-based which means they are completely safe to use with condoms, and only use organic ingredients.   GoLove CBD also offers sex-help books and sex toys to further enhance your time between the sheets.   6.) Kush Queen Rating 3.5/ 5 Extract Type: Isolate Total CBD Range: 30mg Potency Range: 1mg per mL Price Range: $49.99 Value ($/mg): $1.66 per mg THC Content: 0.0% Lab Report: See Here Scent Variations: 1 Potency Variations: 1   Kush Queen Pros: Offers a subscription service to help you save Free shipping on orders of $100 or more   Kush Queen Cons: Low CBD amount (30mg total for 30mL bottle) Much pricier than competitors   Kush Queen often gets mentioned as one of the best CBD lubes for its water-based, latex safe application. As for the lubricant itself, Kush Queen offers one of the best out there and the quality is of the highest standard.   However, in terms of CBD potency, Kush Queen falls a bit flat. Each $49.99 purchase only comes with 30mg total - an amount that many people take with a single dose of CBD. While there is no doubt that this lube can increase pleasure, some customers have mentioned it does not always help with relaxation which may be attributed to its low CBD concentration.   If you are simply looking for a lubricant that can help promote more fun in the bedroom, Kush Queen has you covered. However, if you are looking for a product with therapeutic effects, you may want to check out some of the other lubricants on our list.   What Are CBD Lubes? CBD lubes are lubricants infused with a cannabidiol extract. People use CBD lubes for different reasons all aiming to achieve a better sexual experience, and the most common reason people use CBD lubes is for enhanced sexual arousal. At the same time, many users have also found these products to be beneficial for specific health conditions, such as dryness or menstrual cramps.   CBD lubes will come in three different extract types:   Full-Spectrum - Makes use of all the cannabinoids found in the hemp plant – contains less than 0.3% of tetrahydrocannabinol (THC).   Broad-Spectrum - Makes use of all the cannabinoids found in the hemp plant with the exception of THC.   CBD Isolate - Solely CBD and no other cannabinoid.   While our list of the best CBD lubes contains products with all three extract types, we recommend going with products made with full-spectrum or broad-spectrum extracts. This will allow you to experience what’s known as the entourage effect (which usually enhances the effects on CBD).   Are CBD Lubes Safe? The safety of CBD lube ultimately depends on the ingredients used to make the product. All the products mentioned here are safe to use for sexual activity (this includes oral consumption).   However, it should be noted that not all CBD lubes are safe to use with latex condoms. Those made with certain oils (especially coconut oil) will cause condoms to degrade and breakdown, this will compromise the condom and make it ineffective.   With that said, if you plan to use a CBD lube with a condom, we highly suggest going with a water-based formula. In the event that you are not using a condom, the choice of oil-based or water-based formula will come down to your personal preference.   Why Use CBD Lubricant? In 2017, researchers at Stanford University did a study exploring cannabis use and sexual activity. It was discovered that those who used cannabis were 20% more likely to participate in sexual activity compared to those who did not. This led the researchers to the conclusion that there is a relationship between cannabis consumption and increased levels of sexual arousal and activity.   It is important to note, however, that this study investigated cannabis users who consumed cannabis that included the psychoactive cannabinoid THC. As for CBD in particular, some new research is suggesting it may also help.   In 2009, it was discovered that the endocannabinoid system (ECS) has receptors within various sexual reproductive organs. Therefore, some researchers theorize that phytocannabinoids may increase activity in the libido. However, this is a controversial point and there are currently no definite studies concluding this point.   While researchers continue to investigate CBD’s role effect on sexual activity, we do know for a fact that CBD can help relax the mind and body. Consequently, we can assume that the more relaxed we are, the easier and more enjoyable we will find it to participate in sexual activity.   What Does CBD Lube Do? CBD lube works like any other lubricant. The key difference is it also acts as a CBD topical. Topical products will deliver large concentrations of CBD to a targeted area. In the case of lubricant, this will be the area around our genitals and any other areas we may choose to apply this CBD lube.   After these areas receive a dose of CBD, they will potentially experience one or more of several medical benefits, including:   Dryness Endometriosis Increased blood flow Interstitial cystitis Menopausal symptoms Menstrual cramps Sexual arousal Vaginismus Vulvodynia   So, while more research needs to be done to fully understand how CBD lubricants affect us, numerous reviews of the products mentioned on this list indicate that these lubricants have been intimate game-changers for a lot of people.   Our Criteria for the Best CBD Lube When it comes to developing our list of the best CBD lube, we had a few requirements in mind before choosing the brands and products we included. If you’re considering purchasing CBD lube from a brand outside of our list, we highly suggest you keep this set of criteria in mind:   Certificate of Analysis - These are third-party lab tests that provide unbiased lab results concerning various aspects of the CBD, including its cannabinoid and terpene profile, its purity, and whether or not it contains contaminants such as pesticides.   Extract Type - It is important to understand the three different hemp extract types before making your purchase. They include full-spectrum, broad-spectrum, and isolate. In order to create a diverse list, we included at least one of each on our list.   Ingredients - Genitals are highly sensitive areas. Therefore, it is important to make sure a brand uses safe ingredients that also meet any dietary restrictions.   Potency - While CBD topicals tend to not have as strong an effect as oils or vapes, it remains important to understand how much CBD you are taking in. Each CBD lubricant will have the potency of a product labeled on the front in milligrams (mg). The higher this number, the more potent a product is.   Safety and Side Effects of CBD Lube When it comes to our sexual health, safety should be our number one concern when it comes to CBD lubes. Our genitals are extremely absorbent and, as a result, will be affected by any products we apply to them. For this reason, it is vital to avoid certain ingredients when purchasing a CBD lube. Ingredients to stay away from include:   Glycerin Propylene glycol Benzocaine Silicone Petroleum Parabens Sodium hydroxide Artificial aromas Artificial flavors   While CBD is safe to consume in any area of the body, it is not entirely without side effects. Side effects from CBD are usually mild and only a handful of people report them. They include:   Appetite changes Diarrhea Drowsiness Fatigue   If you are currently on medication, it is important to consult your doctor before taking CBD. While it is rare, some prescription medications have been found to negatively interact with CBD.   Also, if you are pregnant or lactating, we highly suggest avoiding CBD products altogether. There currently is not enough evidence to suggest it’s safe for women of this category to consume CBD.   Frequently Asked Questions Is CBD Lube Safe to Use with Condoms? If the CBD lube is water-based, then it is safe to use with condoms. On the other hand, it should be noted that CBD lube that uses oils (especially coconut oil) can cause condoms to break down.   Is CBD Lube Edible? CBD lube is completely edible and can be consumed when performing oral sexual activity.   Is CBD Lube Only for Women? No! It is completely safe for men to also enjoy the pleasures of CBD lube.   What Ingredients Should I Avoid in CBD Lubes? If you want to use CBD lube with a condom, you should avoid anything that uses oils (especially coconut oil). You should also avoid anything that uses glycerin, propylene glycol, benzocaine, silicone, petroleum, parabens, sodium hydroxide, artificial aromas, and artificial flavors. Keep in mind, if you have any dietary restrictions, you should do some research into these products before using them to make sure they meet your requirements.   Will CBD Lube Get Me High? No! All federally legal CBD products must contain less than 0.3% THC. This amount is so small, it does not produce psychoactivity.