5 Best CBD Cartridges
Top of 2025

What Are CBD Cartridges?

A CBD cartridge is a special chamber that holds hemp extract along with a carrier liquid. Two of the common carrier liquids are vegetable glycerin (VG) and propylene glycol (PG).

In the case of CBD vape cartridges, the most common battery type is the 510 thread. If you don’t already own one of these, all the companies on our list offer an option to purchase one at reasonable prices.

Can You Vape CBD Oil?

 No! CBD oil (also known as tinctures) that most companies sell is not designed for vape cartridges. In fact, they can contain ingredients that are dangerous to inhale. You can only vape CBD e-juices (sometimes referred to as e-liquids or vape juicecs).

Top 5 Best CBD Cartridges

How Do CBD Cartridges Work?

When you use a cartridge, you can expect to experience similar effects to those of other CBD products, such as oils or edibles. However, where vaping CBD is different is the fact that it will produce almost immediate effects. This is thanks to the fact that when we take CBD into our lungs, it’s able to get into our bloodstream quicker.

For this reason, these vape products have been very popular for those who need immediate fixes. For example, people with anxiety find these cartridges are great for the sudden onset of an attack. That said, some people just prefer to inhale CBD and feel drawn to CBD cartridges more than other consumption methods.

You can expect these cartridges to make you feel relaxed and in an overall better mood. It’s worth noting that some of the products on our list include various hemp strains. Certain strains may produce slightly different effects. For example, indica cannabis strains are often associated with relaxing effects whereas sativa cannabis strains will make you more awake and creative.

What Are the Benefits of CBD Cartridges?

What Are the Best Refillable Vape Cartridges?

Refillable CBD cartridges work very similarly to those mentioned on this list. The main difference is that your purchase won’t come pre-filled with cannabidiol vape juice. Instead, you’ll have to purchase the vape juice separately.

A big upside to refillable cartridges is the fact that you can use them over and over again. Since you’re only purchasing vape juice, you’ll likely save money in the long run. Not to mention, refillable cartridges are much more environmentally responsible as they don’t produce as much waste as single-use cartridges.

Currently, CBDfx offers one of the best refillable vape cartridges on the market. Their CBD Vape Kit V2 Cartridge only costs $8.99 and is compatible with most 510 threaded batteries. All you need to do is fill it up with some cannabidiol e-juice (which CBDfx also conveniently sells).

Keep in mind, that when purchasing refillable cartridges, you will still need to also purchase a battery.

CBD Cartridge Dosage Recommendation

It can be difficult to determine the dosage of a CBD cartridge as it varies depending on how many puffs you take. The more you inhale, the more cannabidiol you receive. You can get a sense of the dosage amount through the total cannabidiol amount indicated on the packaging – this will always be listed in milligrams (mg). The higher this number, the higher the amount of CBD per puff.

If you’re new to vaping CBD, you’re likely going to have to experiment before you get a good sense of how much you should inhale. A good way to do this is to take the time to sit back, relax, take a few puffs, and see how these products make you feel. If you’re not receiving the desired effects, gradually increase your dose by taking a few more puffs.

Our Criteria for Best CBD Cartridges

In order to make sure we only recommended the best CBD cartridges, we had a set of requirements each company had to meet in order to be a top-ranker. If you plan to shop for these cartridges yourself, we highly suggest you consider using similar criteria:

Certificate of Analysis (CoA)

Since the industry is unregulated, it is in your best interest to make sure the products you’re consuming are safe and of high quality. One way companies ensure this is by running batches of their CBD extract through a third-party lab test. These will inform you of various aspects of the CBD, including its purity and whether or not it contains any contaminants, such as heavy metals.

Extract Type

Products will come in three different extract types of cannabidiol. It is important to understand these before deciding which product is right for you:

• • Full-Spectrum – Incorporates all of hemp’s cannabinoids and terpenes (will contain less than 0.3% THC).
  • Broad-Spectrum – Incorporates all of hemp’s cannabinoids and terpenes with the exception of THC.
  • Isolate – Purely CBD and no other cannabinoid.

If you’re looking to avoid failing a drug test, we recommend CBD carts with CBD isolate or broad-spectrum extract. To garner an entourage effect from the hemp plant, you should opt for full-spectrum CBD vape carts.

On top of this, we prefer CBD brands that use the standardized CO2 extraction method.

Hemp Source

While this may not be a dealbreaker for all users, we believe in the importance of companies sourcing ethical, local, and organic-grown hemp.

Ingredients

Before purchasing a CBD product, you will want to make sure the ingredients it uses are safe to consume and meet your dietary requirements. This may mean opting for CBD vape oils with natural flavors rather than artificial flavors.

Potency

All CBD products measure their potency using a milligram (mg) count. The higher this number the higher CBD content a certain product contains, making it a more potent product. Newcomers should stick to lower potency products in order to gain an understanding of how CBD affects them.

Safety and Side Effects of CBD Cartridges

While studies have shown that vaping is generally safer than smoking, it remains a new phenomenon that doesn’t have enough research into the potential long-term consequences. Furthermore, there’s always some concern when it comes to inhaling chemicals into our lungs.

This concern was brought into full view in mid-2019 when a number of cannabis vaping products were sending people to hospitals – sometimes with fatal consequences. Researchers have concluded that the reason for this epidemic was Vitamin E acetate – a naturally occurring compound that is found in the body and can be extracted from certain foods. While it is safe to consume Vitamin E through digestion, it’s very dangerous to inhale.

The reason this outbreak occurred is due to less reputable cannabis companies putting out products that didn’t meet safety guidelines. To ensure the safety of our readers, we only included companies on this list that have built both a reputable brand and have ingredients that are safe to consume. No CBD cartridge on our list contains Vitamin E acetate.

Beyond this, CBD does hold the potential to produce side effects. While these are rare, some users have reported feeling mild bouts of:

• Appetite changes
• Diarrhea
• Drowsiness
• Dry mouth
• Fatigue

If you are currently on prescription medication, it is in your best interest to consult your doctor before taking CBD. While it is rare, there have been cases where CBD negatively interacts with certain medications.

Finally, if you are pregnant or lactating, you should avoid taking CBD altogether. Currently, there just is not enough evidence to suggest that it is safe for women of this category to consume CBD products.