Best CBD Vape Juice 2023

Paul James Updated on February 24, 2023 Affiliate Disclosure Some links are specifically formatted for which we may receive a commission on resulting sales or clicks from affiliate partners (“Affiliate Links”).

CBD vape juices come in all shapes and sizes from a number of brands. With that, it can be difficult to determine what are the best CBD vape juices on the market.

Vaping cannabidiol (CBD) is a popular option for cannabis/cigarette smokers and those seeking out new consumption methods. Vaping CBD provides you with the most immediate effects as it’s able to enter your bloodstream quicker. With that, people with certain health conditions – like anxiety – prefer CBD vape products because they allow for near-instant relief.

There are so many CBD vape products on the market that it can be difficult to tell which one is right for you.

It can also be difficult as both the CBD and vape industry are still in their early stages. It can’t be forgotten that nearly a decade ago, both barely had a market. Because it’s all so new, laws and regulations still aren’t finalized. Therefore, you must decide for yourself which products are right for you.

Throughout this article, we’re going to explore all the ins and outs of CBD vaping to give you a comprehensive understanding of what to keep an eye out for. We’ll also list our top picks for the best CBD vape juices.

What is CBD Vape Juice?

If you’ve ever used an e-cigarette or Juul, you’re probably aware of how vaporization works. By taking a substance, making it water-soluble, and applying heat to that soluble, you get a vapor that can be inhaled.

Vaping CBD works almost identically to tobacco water solubles. There are only two major differences:

  1. Instead of nicotine, you receive CBD which comes from the cannabis plant (or the hemp plant) instead of the tobacco plant.
  2. CBD oil is hydrophobic which means it doesn’t like water. Most CBD vape products are formulated to be water-compatible. In turn, they appear water-soluble.


Vaping CBD works a bit differently in comparison to other consumption methods. Since you’re inhaling it into your lungs rather than ingesting it or rubbing it onto your skin, the cannabinoid will enter your bloodstream quicker.

Top 5 Best CBD Vape Juices

Vaping CBD is 50-60% stronger than other consumption methods because cannabinoids enter your bloodstream through your lungs rather than your liver.

Are All CBD Vape Oils the Same?

As discussed, one of the biggest issues with CBD for a vaporizer is that it’s hydrophobic and not a compatible molecule for e-liquid bases. This leaves those formulating CBD vape products in a sticky situation. In many regards, they’re fighting against chemistry in order to make these products available.

Due to this, not all CBD vape liquids are made in the same fashion. With that, it’s vital you look into a CBD vape product you plan to purchase, including its ingredients and how it was made in the laboratory.

As we’ll discuss a bit later, since both the vape and CBD industry are fairly regulated, hazardous products are unfortunately prone to placement on store shelves.

Will CBD Vape Oil Work in Your Vaporizer?

If you’ve been vaping for some time, you’ve probably heard the terms propylene glycol (PG) and vegetable glycerin (VG). To put it simply:

  • Propylene glycol (PG) is a petroleum by-product that provides users with a ‘throat-hit’ that is claimed to feel similar to smoking a cigarette.
  • Vegetable glycerin (VG) is a natural chemical derived from vegetable oils (making it vegan-friendly). It offers a thick and smoother sensation in the throat and lungs.
Will CBD Vape Oil Work in Your Vaporizer?

All e-liquids are infused with vegetable glycerin. However, since CBD tends to be oily, this comes with a few notable downsides.


For one, the oily CBD layer can potentially separate from the vegetable glycerin and cause damage to your vaporizer tank – especially if your tank relies on a cotton wick that soaks up the liquid. Over time, the oily CBD layer will naturally dry up and harden wherever it’s left. So, if it’s been drying in your pen, it may make the tank unusable.


Luckily, there are two ways to avoid this problem:


  1. Purchase a tank with a ceramic heating element.
  2. Purchase a liquid that’s completely homogenized.


Furthermore, there are disposable vape products available that will completely eliminate this problem. The only downside to these is that they’re not recyclable, cannot be refilled, and won’t work with all kinds of vape batteries.

What to Look Out for When Purchasing CBD Vape Juice

When it comes to CBD vape oil, the clearer the juice, the better it is. The cloudier the vape juice, the dirtier (and potentially filled with hazardous material) it is. Luckily, this is something anyone can spot. As soon as you pour a CBD e-liquid into your vape pen, you’ll be able to understand just how clean the product is.

However, in such an unregulated industry, it’s important to keep an eye out for a couple of other potential hazards. You can do so by:

1.) Checking the Product Label Claims

Don’t be fooled! A quick look at a product’s label claims DOES NOT guarantee that the company is trustworthy. There are, unfortunately, many out there fooling consumers into thinking their CBD e-liquid is quality.

Still, this doesn’t mean you shouldn’t look at the product’s label claims. In fact, we encourage you to. Then, to confirm the company’s claims are legitimate, either ask for or seek out test results from a third-party lab.

2.) Looking Into the Source of CBD

Another big issue amongst all CBD products is the source of hemp the CBD comes from. A reputable company will have this information easily available on its website. An illegitimate company may try to avoid providing its customers with this information.

You want to know the source of your CBD extract because other products of industrial hemp have had heavy metals, microbiological contamination, pesticides, and residual solvents. None of these are safe for consumption and may offset the benefits of CBD.

Safety and Side Effects of Vaping CBD E-Juice

CBD vape juice products (including CBD vape pens) are considered to be a safer alternative to smoking cannabis products. Unfortunately, since the vaping industry is just as new as the CBD industry, there are no long-term studies confirming how much safer vaping CBD oil is in comparison to smoking hemp flower.

Not to mention, since the 2019 vape pandemic, there has been a lot of concern around vape products. A number of people who had consumed cannabis vape products were being sent to the hospital, some of which experienced fatal consequences. Research has discovered that the culprit of this pandemic was vitamin E acetate. While this substance is safe to consume, it’s extremely dangerous to inhale.

In order to ensure our readers’ safety, none of the CBD vape juices on our list contain vitamin E acetate or any other dangerous CBD vape additives. And while there have been regulation efforts to ban this substance from vaping products, we highly suggest looking into the ingredients of a CBD vape juice before purchasing.

Vaping CBD Safety and Side Effects

Beyond this, some users have experienced mild bouts of side effects from CBD itself. Common side effects of CBD products include:

  • Appetite changes
  • Diarrhea
  • Drowsiness
  • Dry mouth
  • Fatigue


If you are currently taking prescription medication, we suggest you consult a doctor before inhaling CBD vape juice. Some medications have been found to have negative interactions with CBD.

If you are pregnant or lactating, we suggest avoiding CBD altogether. Currently, there isn’t enough research to suggest CBD is safe for women of this category.

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Paul James

Paul James is a seasoned cannabis and CBD writer and expert. He is a mental health blogger who advocates CBD as a natural alternative to prescription medications. You can read more about this and other natural alternatives on his blog:"

Frequently Asked Questions

Your standard CBD oil tincture should never be mixed with vape juice. While these are safe to digest, CBD oils contain ingredients that are harmful to vaporize and inhale.